Re: Fewer genes than expected

From: Bill Spight (bspight@pacbell.net)
Date: Mon Feb 12 2001 - 16:18:24 GMT

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    Date: Mon, 12 Feb 2001 08:18:24 -0800
    From: Bill Spight <bspight@pacbell.net>
    Subject: Re: Fewer genes than expected
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    Dear Kenneth,

    Here is a quote from the Nature article (Vol. 409, p. 901), on
    www.nature.com.

    > The human thus appears to have only about twice as many genes
    > as worm or fly. However, human genes differ in important respects
    > from those in worm and fly. They are spread out over much larger
    > regions of genomic DNA, and they are used to construct more
    > alternative transcripts. This may result in perhaps five times as many
    > primary protein products in the human as in the worm or fly.

    IOW, gene number is only a gross estimate of phenotypic complexity.

    Ciao,

    Bill

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