From: Derek Gatherer (d.gatherer@vir.gla.ac.uk)
Date: Thu 08 Dec 2005 - 09:23:40 GMT
>The last paragraph of the last message should actually be:
To say that "the more one selects for resistance the more mutants one
finds" (p.214 top) is meaningless, for the above reason, unless one
can show that in cells never exposed to the _selection pressure_,
there are fewer resistant colonies. Since Hill maintains that in
cells never exposed to the _selection pressure_, there are actually
_more_ resistant colonies, this experiment is by definition control-less.
Selection pressure, not mutagen (there is no mutagen in this
experiment, apart from the mutagenic effect probably visible in the
serial assay)
>To say that "the more one selects for resistance the more mutants
>one finds" (p.214 top) is meaningless, for the above reason, unless
>one can show that in cells never exposed to the mutagen, there are
>fewer resistant colonies. Since Hill maintains that in cells never
>exposed to the mutagen, there are actually _more_ resistant
>colonies, this experiment is by definition control-less.
>
>===============================================================
>This was distributed via the memetics list associated with the
>Journal of Memetics - Evolutionary Models of Information Transmission
>For information about the journal and the list (e.g. unsubscribing)
>see: http://www.cpm.mmu.ac.uk/jom-emit
>
===============================================================
This was distributed via the memetics list associated with the
Journal of Memetics - Evolutionary Models of Information Transmission
For information about the journal and the list (e.g. unsubscribing)
see: http://www.cpm.mmu.ac.uk/jom-emit
This archive was generated by hypermail 2.1.5 : Thu 08 Dec 2005 - 09:42:58 GMT