From: derek gatherer (dgatherer2002@yahoo.co.uk)
Date: Mon 28 Jul 2003 - 15:46:02 GMT
The genetic epidemiology of thinness
Obesity Reviews, February 2001, vol. 2, no. 2,
pp. 107-115(9)
Bulik C.M.; Allison D.B.
Abstract:
Summary
Most genetic research in the area of human obesity
asks the question ‘Why are certain people obese?’
Considerably less attention has been paid to the
question of why certain people are not obese,
particularly given the obesogenic environment that
permeates the western culture. We present data from
human and animal studies and evolutionary arguments
supporting the notion that genetic studies of thinness
or obesity resistance may yield important and
complementary findings to genetic studies of obesity.
We offer strategies for further refining the
definition of thinness, weigh the advantages and
disadvantages of potential sampling strategies and
suggest candidate genes for thinness or obesity
resistance.
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